CEFTOLON-SB-187.5
MRP: 41
Packaging: 187.5MG
Pack Type: injection
Composition:
Ceftriaxone Sodium 125mg + Sulbactam 62.5mg
Indication:
Respiratory Tract Infections, Bacterial Septicemia, Skin & Soft Tissue Infections, Urinary Tract Infections, Meningitis, Pelvic Inflammatory Diseases.
Description:
Ceftriaxone Sodium 125mg + Sulbactam 62.5mg is a beta-lactam/beta-lactamase inhibitor combination antibiotic. Ceftriaxone is a third-generation cephalosporin with broad-spectrum bactericidal activity, while Sulbactam is a beta-lactamase inhibitor that enhances Ceftriaxone's effectiveness against resistant bacteria by neutralizing beta-lactamase enzymes.
This combination is typically used in pediatric patients or those requiring a low-dose regimen for infections such as lower respiratory tract infections, skin and soft tissue infections, urinary tract infections, ENT infections, bone and joint infections, and intra-abdominal infections.
Tags:
- Well-tolerated with broad clinical use
- Once-daily dosing due to long half-life
- Suitable for pediatric or low-weight patients
- Sulbactam improves efficacy against resistant strains
- Effective against both gram-positive and gram-negative bacteria
Usage Information
Dosage
Pediatric Dose: Adjusted per body weight; commonly 30–50 mg/kg/day in divided doses Route: Intravenous (IV) or Intramuscular (IM) injection Frequency: Once or twice daily as per clinical severity Dilution: Reconstitute with sterile water for injection as directed on label
Side Effects
Local pain or swelling at injection site Rash, allergic reactions Diarrhea or gastrointestinal discomfort Elevated liver enzymes Rare: Hemolytic anemia, thrombocytopenia
Contraindications
Hypersensitivity to cephalosporins or penicillins Neonates with hyperbilirubinemia (risk of kernicterus) Use cautiously in patients with severe renal impairment Avoid mixing with calcium-containing solutions (especially in neonates)