MORBIFIX-SB 375
MRP: 50
Packaging: 375mg
Pack Type: injection
Composition:
Ceftriaxone Sodium 250mg + Sulbactam 125mg
Indication:
Typhoid Fever - Septicemia - Pneumonia - Meningitis - Bacteremia - UTIs
Description:
This combination includes:
Ceftriaxone Sodium (250mg): A broad-spectrum third-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis.
Sulbactam (125mg): A beta-lactamase inhibitor that protects ceftriaxone from degradation by resistant bacteria, thereby enhancing its antibacterial effect.
Together, they provide powerful action against a broad range of gram-positive and gram-negative bacteria, including many drug-resistant strains. It is administered parenterally (via injection) and is used in moderate to severe infections.
Tags:
- Effective against beta-lactamase producing bacteria
- Broad-spectrum action for complex infections
- Enhanced efficacy with Sulbactam addition
- Used in both community and hospital-acquired infections
- Convenient once or twice daily dosing
Usage Information
Dosage
Route: Intramuscular (IM) or Intravenous (IV) injection Adults: Typically 1–2 grams/day, divided doses Pediatric: Adjusted by weight, usually 50–75 mg/kg/day Frequency: Once or twice daily as directed by physician Reconstitution: With sterile water or WFI as per label instructions
Side Effects
Common: Pain at injection site Diarrhea Rash Nausea Serious (rare): Severe allergic reactions Clostridium difficile-associated diarrhea Liver enzyme abnormalities Blood disorders (anemia, leukopenia)
Contraindications
Do NOT use in: Known allergy to cephalosporins or penicillins Neonates with hyperbilirubinemia (especially preterm) Patients with severe hepatic or renal dysfunction without dose adjustment Concurrent use with calcium-containing IV solutions in neonates
Availability
Ceftriaxone Sulbactam Injection uses Ceftriaxone 250mg + Sulbactam 125mg Broad spectrum antibiotic injection Injectable antibiotic for resistant infections Cephalosporin with beta-lactamase inhibitor