DULONOR-P
MRP: 1,150
Packaging: 10x10
Pack Type: tablet
Composition:
Propranolol 40mg + Flunarizine 5mg
Indication:
Migraine, Prophylaxis of peripheral & CV disorders.
Description:
This combination of Propranolol, a beta-blocker, and Flunarizine, a calcium channel blocker, is formulated to provide enhanced prophylaxis against migraine headaches. Propranolol works by reducing the heart rate and blood pressure, stabilizing vascular tone, while Flunarizine prevents excessive calcium entry in neurons, thus reducing migraine frequency and intensity. The dual-action makes it highly effective in chronic migraine management, especially in patients unresponsive to monotherapy.
Tags:
- Reduces migraine frequency and severity
- Ideal for chronic or treatment-resistant migraines
- Dual mechanism: vascular tone + neuronal stability
- May help improve quality of life in migraine sufferers
- Better control than single-agent therapy
Usage Information
Dosage
Usual Adult Dose: One tablet (40mg/5mg) once or twice daily, as prescribed Take after meals to minimize gastric upset Continue for at least 8–12 weeks for optimal results Do not discontinue abruptly without doctor’s advice
Side Effects
Common Side Effects: Fatigue, dizziness Weight gain Sleepiness Slow heart rate Less Common: Depression or mood changes Gastrointestinal disturbances Cold extremities
Contraindications
Asthma or bronchospasm Bradycardia or AV block Depression history Heart failure Severe liver disease