COOL-TIME
MRP: 75
Packaging: 30 ml
Pack Type: syrup
Composition:
Granisetron 1mg
Indication:
Treatment of post-operative nausea and vomiting in adults. Nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin. Nausea and vomiting associated with radiation.
Description:
Granisetron 1 mg is a selective 5-HT3 receptor antagonist used to prevent and treat nausea and vomiting associated with chemotherapy, radiotherapy, and surgery. It works by blocking serotonin receptors in the brain and gastrointestinal tract, which are responsible for triggering nausea and vomiting reflexes.
This injectable formulation offers rapid onset and is ideal for hospital and clinical settings, especially during oncology or postoperative care.
Tags:
- Effective antiemetic for chemo, radiation, and post-op care
- Rapid onset of action and long-lasting relief
- Minimal sedation or extrapyramidal side effects
- Well tolerated in both adults and children
- Can reduce need for additional rescue medications
Usage Information
Dosage
Route: Intravenous (IV) or Intramuscular (IM) injection Adult (chemo/radio-induced N/V): 1 mg once or twice daily, usually before therapy Postoperative nausea/vomiting (PONV): 1 mg as a single dose before anesthesia or surgery Pediatric use: Dose based on body weight (approx. 20–40 mcg/kg), consult physician Always follow hospital or physician-specific guidelines May be diluted and infused slowly over 5 minutes
Side Effects
Headache (most common) Constipation Injection site irritation Dizziness or fatigue Rare: ECG changes (QT prolongation), hypersensitivity reactions
Contraindications
Known hypersensitivity to Granisetron or other 5-HT3 antagonists Use with caution in patients with cardiac arrhythmias or on QT-prolonging drugs Not recommended for use in pregnancy without medical advice Avoid mixing with other IV drugs unless compatibility is confirmed
Availability
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