NITOPURE-100 SR
MRP: 1,130
Packaging: 10x14
Pack Type: tablet
Composition:
Nitrofurantoin 100mg Sustained Release
Indication:
Nitrofurantoin is used to treat urinary tract infections, Nitrofurantoin remains a reliable first-line agent fir the empirical treatment of acute uncomplicated cystitis
Description:
Nitrofurantoin 100 mg SR is a broad-spectrum antibacterial agent used primarily for the treatment and prevention of urinary tract infections (UTIs) caused by susceptible strains of Escherichia coli, Enterococci, Staphylococci, and other urinary pathogens.
This sustained-release (SR) formulation allows for prolonged therapeutic levels in the urine, enabling twice-daily dosing, improving compliance, and reducing gastrointestinal side effects compared to immediate-release formulations.
Tags:
- Effective treatment for acute and chronic urinary tract infections
- Sustained-release action ensures longer urine concentrations
- Reduces dosing frequency to twice daily, improving compliance
- Lower incidence of gastrointestinal side effects than IR formulations
- Bactericidal action against both gram-positive and gram-negative urinary pathogens
Usage Information
Dosage
Typical Adult Dose: 100 mg twice daily for 5–7 days Take with food to enhance absorption and reduce stomach upset Duration may vary based on clinical indication and physician advice
Side Effects
Common: Nausea, headache, flatulence, dark-colored urine Rare: Pulmonary reactions (acute/chronic), liver enzyme elevation, neuropathy Long-term use may lead to peripheral neuropathy or pulmonary toxicity
Contraindications
Known hypersensitivity to nitrofurantoin Renal impairment (CrCl < 60 mL/min in some guidelines) Pregnancy (near term: risk of hemolytic anemia in neonates) Neonates < 1 month old Patients with a history of hepatic dysfunction associated with prior nitrofurantoin use
Availability
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