MIRDOT-S 50/5
MRP: 4,900
Packaging: 10x10
Pack Type: tablet
Composition:
Mirabegron 5 mg (as extended release form) + Solifenacin Succinate IP 5mg
Indication:
Treatment of OAB symptoms of urge urinary incontinence, urgency, and urinary frequency
Description:
This combination tablet contains Mirabegron, a beta-3 adrenergic receptor agonist, and Solifenacin Succinate, a muscarinic receptor antagonist. It is used for the management of Overactive Bladder (OAB) with symptoms such as urinary urgency, increased frequency, and urge incontinence.
Mirabegron (5 mg ER) works by relaxing bladder muscles to increase bladder capacity.
Solifenacin (5 mg) reduces bladder spasms by blocking muscarinic receptors, thereby decreasing urgency and leakage.
This dual-action formulation provides synergistic efficacy by targeting both the adrenergic and cholinergic pathways of bladder control.
Tags:
- Comprehensive control of OAB symptoms (urgency, frequency, incontinence)
- Dual mechanism targets both smooth muscle relaxation and bladder spasms
- Improves bladder capacity and reduces leakage episodes
- Enhances patient compliance with once-daily dosing
- Proven efficacy in clinical trials for OAB management
Usage Information
Dosage
Adults: One tablet once daily, taken with water, preferably at the same time each day Do not crush or chew—swallow whole Dose may be adjusted based on individual response and tolerability Use only under medical supervision, especially in elderly patients or those with kidney/liver impairment
Side Effects
Dry mouth Constipation Headache Increased blood pressure Urinary tract infection Rare: Angioedema, blurred vision, palpitations
Contraindications
Urinary retention Gastric retention or uncontrolled narrow-angle glaucoma Severe hepatic or renal impairment (without dose adjustment) Known hypersensitivity to either component Patients with prolonged QT interval (use with caution)
Availability
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