TEICOINTRA 400
MRP: 1,990
Packaging: 400mg
Pack Type: injection
Composition:
Teicoplanin IP 400mg
Indication:
This allows holes in the bacterial cell wall, which kills the bacteria. Thus, helps in treating and preventing the spread of infections
Description:
Teicoplanin IP 400 mg is a broad-spectrum glycopeptide antibiotic indicated for the treatment of severe Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus species. It works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death.
It is used as an alternative to Vancomycin due to its longer half-life, lower nephrotoxicity, and once-daily dosing regimen. It is effective against:
MRSA infections
Bloodstream infections (septicemia, bacteremia)
Respiratory tract infections
Bone and joint infections
Skin and soft tissue infections
Endocarditis
Post-surgical and ICU-acquired infections
Teicoplanin can be administered intravenously (IV) or intramuscularly (IM).
Tags:
- Strong efficacy against MRSA and resistant Gram-positive pathogens
- Less nephrotoxic than Vancomycin
- Convenient once-daily dosing after loading
- Suitable for IV and IM use
- Can be used in outpatient and hospital settings
Usage Information
Dosage
Loading Dose (for serious infections): 400 mg every 12 hours for 3 doses (or 6–12 mg/kg every 12 hrs x 3 doses) Maintenance Dose: 400 mg once daily (or 6–12 mg/kg once daily) Pediatric Dose: Adjusted by weight; under supervision of a specialist Duration: Depends on infection; typically 7–14 days Note: Adjust in renal impairment
Side Effects
Common: Rash or skin redness Nausea or GI discomfort Injection site pain Serious (rare): Nephrotoxicity (less than Vancomycin) Ototoxicity (hearing loss) Blood dyscrasias (leukopenia, thrombocytopenia) Anaphylaxis or hypersensitivity
Contraindications
Known allergy to Teicoplanin or other glycopeptide antibiotics Use with caution in renal impairment Avoid during pregnancy unless absolutely necessary Monitor during long-term therapy (>10 days)