TEICOINTRA 200
MRP: 1,250
Packaging: 200mg
Pack Type: injection
Composition:
Teicoplanin IP 200mg
Indication:
This allows holes in the bacterial cell wall, which kills the bacteria. Thus, helps in treating and preventing the spread of infections
Description:
Teicoplanin IP 200 mg is a glycopeptide antibiotic used to treat serious Gram-positive bacterial infections, including those caused by methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus species. It inhibits bacterial cell wall synthesis, resulting in bactericidal action.
Teicoplanin has a long half-life, allowing once-daily dosing, and can be administered via intravenous (IV) or intramuscular (IM) routes. It is often used as an alternative to Vancomycin, especially in patients at risk of nephrotoxicity.
Indications include:
Bone and joint infections
Skin and soft tissue infections
Bloodstream infections (bacteremia, septicemia)
Endocarditis
Respiratory tract infections
MRSA and multi-drug resistant infections
Tags:
- Effective against MRSA and resistant Gram-positive infections
- Low nephrotoxicity, safer for kidney-impaired patients
- Low nephrotoxicity, safer for kidney-impaired patients Once-daily dosing after loading, improving compliance
- Can be given IV or IM
- Well tolerated with fewer infusion-related reactions
Usage Information
Dosage
Loading Dose: 400 mg every 12 hours for 3 doses (for serious infections) For mild infections: 6 mg/kg every 12 hours for 3 doses Maintenance Dose: 200 mg once daily (or 6–12 mg/kg/day IV/IM) Duration: Usually 7–14 days depending on the infection type and response Note: Adjust dose in patients with renal impairment.
Side Effects
Common: Injection site pain Rash, pruritus Gastrointestinal upset Serious (rare): Ototoxicity Nephrotoxicity (lower than Vancomycin) Blood dyscrasias (thrombocytopenia, neutropenia) Hypersensitivity reactions
Contraindications
Known allergy to Teicoplanin or other glycopeptides Caution in patients with renal impairment or those on nephrotoxic drugs Not recommended during pregnancy unless necessary Monitor in long-term use (>10 days) for blood count and renal function