INTRAMYCIN 500 INJ
MRP: 325
Packaging: 500MG
Pack Type: injection
Composition:
Vancomycin Hydrochloride 500mg
Indication:
Complicated skin infections, Bloodstream infections, Meningitis, Bone & joint infections, Endocarditis
Description:
Vancomycin Hydrochloride 500 mg is a glycopeptide antibiotic primarily used to treat serious Gram-positive bacterial infections, including those caused by methicillin-resistant Staphylococcus aureus (MRSA). It functions by inhibiting bacterial cell wall synthesis, leading to the death of susceptible bacteria.
This injectable antibiotic is administered intravenously for systemic infections such as:
Severe bloodstream infections (bacteremia)
Pneumonia, including hospital-acquired and ventilator-associated
Endocarditis
Bone and joint infections
Skin and soft tissue infections
Clostridioides difficile colitis (oral form only)
Vancomycin 500 mg is often used in hospitalized patients requiring potent antibiotic therapy and is dosed based on patient weight and kidney function.
Tags:
- Highly effective against resistant Gram-positive bacteria like MRSA
- Essential in treating life-threatening infections
- Suitable for complicated skin, bloodstream, bone, and lung infections
- Administered in controlled hospital settings for safety
- Proven clinical efficacy and safety profile with monitoring
Usage Information
Dosage
Typical dose: 15–20 mg/kg every 8–12 hours IV Usual single dose around 500 mg (adjusted based on weight and infection) Infuse slowly over 60 to 90 minutes to reduce infusion reactions Dose adjustment needed in renal impairment Therapeutic drug monitoring recommended
Side Effects
Common: Red man syndrome (flushing, rash during infusion) Injection site reactions (phlebitis) Nausea, fever Serious (rare): Kidney toxicity Hearing loss (ototoxicity) Blood disorders (neutropenia, thrombocytopenia) Allergic reactions
Contraindications
Allergy to Vancomycin or glycopeptide antibiotics Rapid IV infusion (risk of Red man syndrome) Severe renal impairment without monitoring Concurrent use with other nephrotoxic drugs without caution