INTRAMYCIN 1000
MRP: 494
Packaging: 1000MG
Pack Type: injection
Composition:
Vancomycin Hydrochloride 1000mg
Indication:
Complicated skin infections, Bloodstream infections, Meningitis, Bone & joint infections, Endocarditis
Description:
Vancomycin Hydrochloride 1000 mg is a glycopeptide antibiotic used to treat serious or life-threatening bacterial infections caused by Gram-positive organisms, including methicillin-resistant Staphylococcus aureus (MRSA). It works by inhibiting bacterial cell wall synthesis, leading to bacterial death.
It is administered intravenously (IV) for systemic infections and orally (at lower doses) only for intestinal infections like Clostridioides difficile colitis.
Common indications include:
MRSA infections
Sepsis and bacteremia
Pneumonia (hospital-acquired or ventilator-associated)
Bone and joint infections
Endocarditis
Meningitis
Tags:
- Highly effective against MRSA and multidrug-resistant Gram-positive bacteria
- Used in severe, life-threatening infections
- Effective for bloodstream, lung, bone, and CNS infections
- Time-tested antibiotic with a defined therapeutic range
- Administered in hospitals with careful monitoring
Usage Information
Dosage
Standard adult dose: 15–20 mg/kg every 8–12 hours IV Maximum single dose: Usually 1000 mg; may be adjusted per weight and infection type Route: Slow IV infusion over 60–90 minutes Adjust dose in renal impairment Trough level (target): 10–20 mcg/mL (infection-specific)
Side Effects
Common: Red man syndrome (flushing, rash during rapid infusion) Nausea Phlebitis at injection site Fever or chills Serious (Rare): Nephrotoxicity (kidney damage) Ototoxicity (hearing loss) Neutropenia or thrombocytopenia Hypersensitivity reactions
Contraindications
Known hypersensitivity to Vancomycin Rapid IV infusion (risk of Red man syndrome) Severe renal impairment without monitoring Concurrent use with other nephrotoxic or ototoxic drugs (e.g., aminoglycosides) without caution