ZIMIPAR-AV 2.5 INJ.
MRP: 4,500
Packaging: 2.5GM
Pack Type: injection
Composition:
Ceftazidime 2000mg + Avibactam 500mg
Indication:
To treat abdominal (stomach area) infections. It is also used to treat pneumonia that developed in people who are on ventilators or who were in a hospital, and kidney and urinary tract infections.
Description:
Ceftazidime 2000mg + Avibactam 500mg is a combination of a third-generation cephalosporin antibiotic (Ceftazidime) and a non-β-lactam β-lactamase inhibitor (Avibactam). This powerful combination is used to treat complex, multidrug-resistant gram-negative bacterial infections. It is especially effective in treating hospital-acquired pneumonia, complicated intra-abdominal infections, and complicated urinary tract infections caused by resistant strains, including Enterobacteriaceae and Pseudomonas aeruginosa.
Avibactam enhances the effectiveness of Ceftazidime by inhibiting bacterial β-lactamase enzymes that would normally inactivate the antibiotic, thus extending its spectrum against resistant organisms.
Tags:
- Treats life-threatening, multidrug-resistant infections
- Effective against extended-spectrum β-lactamase (ESBL) and KPC-producing organisms
- Synergistic action improves bacterial killing and resistance coverage
- Safe for use in adults with proper renal function monitoring
- Administered in controlled hospital settings for critical infections
Usage Information
Dosage
Typical Dose: 2g Ceftazidime + 0.5g Avibactam every 8 hours Route: Intravenous (IV) infusion over 2 hours Duration: Typically 5–14 days depending on the infection and patient response Note: Dosage must be adjusted for patients with impaired renal function
Side Effects
Nausea, vomiting, or diarrhea Infusion site reactions Headache or dizziness Increased liver enzymes Rash or allergic reactions Rare: Seizures, especially in renal impairment Superinfection with prolonged use
Contraindications
Known hypersensitivity to cephalosporins or Avibactam Severe allergic reactions to beta-lactam antibiotics Not recommended in patients under 18 years unless prescribed by a specialist Use with caution in renal-impaired or seizure-prone patients
Availability
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