TAZOBID
MRP: 447
Packaging: 4.5 GM
Pack Type: injection
Composition:
Tazobactam 0.5g + Piperacillin 4.0g
Indication:
Pneumonia & Bronchitis, Post Surgical Condition, Urinary Tract Infection, Skin & Soft Tissue Infection, Bacteremia & Septicemia, Pneumonia & Bronchitis.
Description:
Tazobactam 0.5g + Piperacillin 4.0g Injection is a broad-spectrum beta-lactam/beta-lactamase inhibitor combination used to treat severe bacterial infections caused by both Gram-positive and Gram-negative organisms including Pseudomonas aeruginosa.
Piperacillin is an extended-spectrum penicillin antibiotic effective against a wide range of bacteria, while Tazobactam inhibits beta-lactamase enzymes produced by bacteria that would otherwise degrade piperacillin, thus enhancing its efficacy.
This combination is commonly used in hospital settings for complicated urinary tract infections, intra-abdominal infections, pneumonia, sepsis, and skin infections.
Tags:
- Broad-spectrum coverage against Gram-positive and Gram-negative bacteria
- Effective against beta-lactamase producing resistant strains
- Treats complicated infections including pneumonia, sepsis, and UTIs
- Enhances efficacy of piperacillin with tazobactam’s beta-lactamase inhibition
- Suitable for critically ill patients requiring IV antibiotics
Usage Information
Dosage
Route: Intravenous (IV) infusion Dose: Adults: 3.375g to 4.5g every 6-8 hours depending on severity and infection type Infuse over 30 minutes Dose adjustments required for renal impairment Administer under medical supervision
Side Effects
Allergic reactions (rash, itching, anaphylaxis) Nausea, vomiting, diarrhea Injection site reactions Electrolyte imbalance Rare: Seizures (especially in renal impairment)
Contraindications
Known hypersensitivity to penicillins, cephalosporins, or beta-lactamase inhibitors Caution in patients with history of allergy to beta-lactam antibiotics Adjust dose in renal impairment to prevent toxicity
Availability
Tazobactam Piperacillin injection Broad-spectrum antibiotic injection Piperacillin Tazobactam 4g/0.5g Beta-lactamase inhibitor combo Injectable antibiotic for severe infections