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DORIFAST-TZ 1125 - Cefoperazone 500mg + Sulbactam 500mg | Intralife Pharmaceuticals
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DORIFAST-TZ 1125

MRP: 460

Packaging: 1125mg

Pack Type: injection

Composition:

Cefoperazone 500mg + Sulbactam 500mg

Indication:

Intra-Abdomi nal Infection, Severe Hospitalised Patients, Gynae, Obstetric Infections, Burns & Wounds, Meningitis, Surgical Infection.

Description:

Cefoperazone + Sulbactam is a combination antibiotic used to treat a wide range of moderate to severe bacterial infections. Cefoperazone, a third-generation cephalosporin, disrupts bacterial cell wall synthesis, leading to cell death. However, certain bacteria produce β-lactamase enzymes, which can neutralize Cefoperazone. Sulbactam counters this by inhibiting β-lactamase, thus restoring and enhancing Cefoperazone’s antibacterial effect.

The 1:1 ratio (500mg each) makes this dose particularly effective for moderate infections and useful in outpatient and inpatient care.

Tags:

Antibiotics Injectable Antibiotics Cephalosporins Prescription Drugs Hospital Use Respiratory Infections Urinary Infections Skin Infections
  • Combats Gram-positive & Gram-negative bacteria
  • Effective in β-lactamase-producing organisms
  • Targets UTIs, pneumonia, intra-abdominal & skin infections
  • Lower dose ideal for moderate infections
  • Useful in ambulatory care or step-down therapy
  • Rapid symptom relief when given intravenously or intramuscularly

Usage Information

Dosage

Route: IV (Intravenous) or IM (Intramuscular) Adult Dosage: Usually 1–2g/day in divided doses (500mg + 500mg twice daily) Adjust dose in patients with renal or liver impairment Must be administered by a qualified medical professional Full course to be completed as prescribed

Side Effects

Mild gastrointestinal disturbances (nausea, diarrhea) Local injection site pain or swelling Rash or allergic skin reactions Elevated liver enzymes in rare cases Rare: Thrombocytopenia, neutropenia, overgrowth of non-susceptible bacteria

Contraindications

Allergy to cephalosporins or penicillins Severe hepatic dysfunction or active liver disease Neonates with hyperbilirubinemia Not recommended with calcium-containing IV solutions Caution in pregnant or breastfeeding women (consult physician)

Availability

Cefoperazone 500mg Sulbactam 500mg injection Cephalosporin + beta-lactamase inhibitor Injectable antibiotic for UTI, LRTI Sulbactam with Cefoperazone 1:1 dose Hospital use injectable antibiotic IV antibiotic for skin infections Antibiotic for intra-abdominal infections Broad-spectrum cefoperazone sulbactam Beta-lactam resistant bacteria treatment