DORIFAST-SB-1000
MRP: 205
Packaging: 1 GM
Pack Type: injection
Composition:
Cefoperazone 1000mg + Sulbactam 500mg
Indication:
Urogenital Infections, LRTI Surgical Infections, Necrotic Wounds, Deep Burns.
Description:
Cefoperazone 1000mg + Sulbactam 500mg is a broad-spectrum injectable antibiotic combination used to treat moderate to severe bacterial infections. Cefoperazone is a third-generation cephalosporin that inhibits bacterial cell wall synthesis. However, certain bacteria produce β-lactamase enzymes that deactivate cefoperazone. Sulbactam, a β-lactamase inhibitor, prevents this breakdown, thereby restoring cefoperazone's antibacterial efficacy.
This synergistic combination is effective against Gram-positive, Gram-negative, and β-lactamase-producing bacteria and is commonly used in hospitalized patients for critical infections.
Tags:
- Broad-spectrum antibacterial activity
- Effective against β-lactamase-producing bacteria
- Suitable for use in hospital and ICU settings
- Treats serious infections including: Pneumonia UTI Septicemia Intra-abdominal infections Gynecological infections
- Well-tolerated with high clinical success
Usage Information
Dosage
Route: Intravenous (IV) or Intramuscular (IM) Adult Dose: Commonly 1.5g to 3g/day in 2 divided doses Adjust based on infection severity, renal/hepatic function Administration: Reconstitute with sterile water for injection before use Administer under medical supervision only Duration: As prescribed by physician; typically 7–14 days
Side Effects
Injection site reactions (pain, redness, swelling) Diarrhea or gastrointestinal discomfort Hypersensitivity (rash, itching) Elevated liver enzymes Rare: Superinfection, thrombocytopenia, clotting disorders
Contraindications
Hypersensitivity to cephalosporins or penicillin antibiotics Severe hepatic dysfunction (use with caution) Neonates with hyperbilirubinemia Patients receiving calcium-containing IV fluids (risk of precipitate) Use with caution in pregnancy or lactation
Availability
Cefoperazone Sulbactam 1.5gm Injection Broad-spectrum antibiotic injection Cephalosporin with beta-lactamase inhibitor Cefoperazone + Sulbactam for UTI Hospital-grade antibiotic for ICU Injectable antibiotic for pneumonia Antibiotic for respiratory infections Cefoperazone Sulbactam vial uses IV antibiotic for severe infections