Why is Sulbactam combined with Ceftriaxone?

To inhibit beta-lactamase enzymes and restore Ceftriaxone's antibacterial activity.

Can this combination treat resistant infections?

Yes, especially those caused by beta-lactamase-producing organisms.

Is it safe during pregnancy?

Generally considered safe (Pregnancy Category B), but only under a doctor’s advice.

Can it be used in children?

Yes, in pediatric doses prescribed by a physician.

Is hospitalization required for administration?

Not always. It can be administered in clinical settings with trained professionals.

Ceftriaxone 1g + Sulbactam 500mg | Injection for Infections | Intralife Pharmaceuticals

Name: CEFTOLON-SB 1.5 GM
Brand: Intralife
SKU: -NzIE9PxPxLRkK8RgOi_
Price: 165 INR
Availability: InStock

CEFTOLON-SB 1.5 GM

MRP: 165

Packaging: 1.5 GM

Pack Type: injection

Composition:

Ceftriaxone Sodium 1000 + Sulbactam 500mg

Indication:

Respiratory Tract Infections, Bacterial Septicemia, Skin & Soft Tissue Infections, Urinary Tract Infections, Meningitis, Pelvic Inflammatory Diseases.

Description:

Ceftriaxone + Sulbactam is a synergistic combination of a broad-spectrum third-generation cephalosporin (Ceftriaxone) with a beta-lactamase inhibitor (Sulbactam). This dual action combats beta-lactamase-producing bacteria that are resistant to cephalosporin monotherapy.

Used to treat:

Lower respiratory tract infections
Urinary tract infections (UTIs)
Intra-abdominal infections
Skin and soft tissue infections
Bone and joint infections
Gynecological infections
Sepsis and surgical prophylaxis

Tags:

Injectable Antibiotics Beta-lactamase Inhibitor Combinations Cephalosporins Broad Spectrum Hospital Use

Usage Information

Dosage

Route: Intravenous (IV) or Intramuscular (IM) Adults: 1.5 g once or twice daily depending on severity Children: Dose based on body weight and clinical condition Duration: As prescribed by a physician (typically 5–14 days) Note: Must be administered under medical supervision. Adjust dose in renal impairment.

Side Effects

Common: Local pain/swelling at injection site Nausea, diarrhea Mild rash Elevated liver enzymes Rare/Serious: Hypersensitivity reactions Superinfection (prolonged use) Blood disorders Seizures (especially in renal impairment)

Contraindications

Known allergy to cephalosporins or beta-lactams Severe penicillin hypersensitivity Neonates with hyperbilirubinemia (risk of kernicterus) Concomitant calcium-containing IV solutions in neonates