What is this medication used for?

It's used to treat type 2 diabetes in patients who need more than dual therapy for effective blood sugar control.

How does this combination work?

It works by stimulating insulin release (Glimepiride), improving insulin sensitivity (Pioglitazone), and reducing glucose production (Metformin SR).

When should this tablet be taken?

Typically once daily with a main meal, usually breakfast, or as directed by the doctor.

Is this combination suitable for newly diagnosed diabetics?

It is generally used in patients who have failed to achieve control with dual therapy.

Can it be combined with insulin or other medications?

Only under medical supervision to avoid the risk of hypoglycemia or other adverse effects.

Glimepiride 2mg + Pioglitazone 15mg + Metformin 500mg SR Tablet | Intralife Pharmaceuticals

Name: SUGAMIDE-PM-2
Brand: Intralife
SKU: -NzIBf5ZVt32YE6UqBz0
Price: 1170 INR
Availability: InStock

SUGAMIDE-PM-2

MRP: 1,170

Packaging: 10x15

Pack Type: tablet

Composition:

Glimepiride 2mg +Pioglitazone 15mg + Metformin 500mg (In SR)

Indication:

Type 2 Diabetes

Description:

This triple combination tablet contains Glimepiride 2 mg, Pioglitazone 15 mg, and Metformin Hydrochloride 500 mg in Sustained Release (SR) form. It is formulated to provide comprehensive glycemic control in patients with type 2 diabetes mellitus, especially those not adequately managed by dual therapy.

Glimepiride is a sulfonylurea that stimulates insulin secretion from pancreatic beta cells.
Pioglitazone is a thiazolidinedione (TZD) that improves insulin sensitivity in muscle and adipose tissues.
Metformin SR decreases hepatic glucose production and increases peripheral glucose uptake with prolonged action for better GI tolerance.

This synergistic combination acts through complementary mechanisms to regulate both fasting and postprandial blood glucose levels, making it ideal for advanced cases of type 2 diabetes.

Tags:

Type 2 Diabetes Triple Combination Therapy Oral Antidiabetics Sustained Release High Efficacy

Usage Information

Dosage

Recommended dose: One tablet once daily with food (preferably breakfast) Swallow whole; do not split, chew, or crush Individual dosing must be guided by a physician based on blood glucose monitoring Maintain regular follow-up for dose adjustments

Side Effects

Hypoglycemia (especially if meals are skipped) Gastrointestinal discomfort: nausea, bloating, diarrhea (due to Metformin) Weight gain, edema (from Pioglitazone) Dizziness, headache Rarely: lactic acidosis, liver enzyme elevation

Contraindications

Type 1 diabetes or diabetic ketoacidosis Severe renal or hepatic impairment Cardiac failure (especially NYHA class III or IV) Hypersensitivity to sulfonylureas, thiazolidinediones, or Metformin Bladder cancer history (Pioglitazone caution) Pregnancy or lactation (unless prescribed) Alcoholism or conditions with increased lactic acidosis risk