What is the purpose of this combination?

It offers dual action—Glimepiride increases insulin secretion; Metformin SR maintains long-term glucose control.

Why is Metformin in sustained-release form?

To provide prolonged blood sugar control and reduce gastrointestinal side effects.

When should I take this medication?

Usually taken once daily with food, preferably breakfast or the first main meal.

Is this suitable for newly diagnosed patients?

It’s more often prescribed to those not adequately controlled with monotherapy.

Can this medicine cause low blood sugar?

Yes, mainly due to Glimepiride. Always take it with meals and monitor glucose levels regularly.

Glimepiride 1mg + Metformin 1000mg SR Tablets | Intralife Pharmaceuticals

Name: SUGAMIDE-M1 1000
Brand: Intralife
SKU: -NzIBf0iGqhMX7XeMsVV
Price: 870 INR
Availability: InStock

SUGAMIDE-M1 1000

MRP: 870

Packaging: 10x10

Pack Type: tablet

Composition:

Glimepiride 1mg + metformin 1000mg in SR,

Indication:

Glimepiride 1mg

Description:

This fixed-dose combination tablet contains Glimepiride 1 mg (a sulfonylurea) and Metformin Hydrochloride 1000 mg in sustained release (SR) form. It is designed for effective long-term management of type 2 diabetes mellitus in adults.

Glimepiride works by stimulating insulin secretion from the pancreas, thereby lowering blood glucose quickly.
Metformin SR provides prolonged control over blood glucose levels by reducing hepatic glucose output, enhancing peripheral glucose uptake, and lowering intestinal glucose absorption.

The sustained-release formulation of Metformin ensures extended efficacy, improved gastrointestinal tolerance, and better compliance in patients requiring higher doses of Metformin.

This combination is typically used when monotherapy does not achieve adequate glycemic control.

Tags:

Type 2 Diabetes Oral Antidiabetics Sustained Release Tablets Sulfonylurea + Biguanide Prescription Only

Usage Information

Dosage

Recommended dose: One tablet daily with food, usually breakfast Swallow the tablet whole with water; do not split, crush, or chew Dosage may be adjusted based on individual response and physician’s advice Avoid skipping meals to reduce the risk of hypoglycemia

Side Effects

Hypoglycemia (especially if meals are missed) Gastrointestinal discomfort (nausea, diarrhea, bloating) Headache or dizziness Mild weight gain (from Glimepiride) Rare risk of lactic acidosis (linked to high-dose Metformin in renal impairment)

Contraindications

Type 1 diabetes Diabetic ketoacidosis Severe renal or hepatic dysfunction Allergy to Glimepiride, Metformin, or sulfonylureas Alcohol abuse, dehydration, heart failure Pregnancy or lactation unless advised by a healthcare professional