
SUGAMIDE-M-1 Tablet
MRP: 735
Packaging: 10x15
Pack Type: tablet
Composition:
Glimepiride 1mg + Metformin 500mg (Bi Layer Tablet) (In SR)
Indication:
Metformin and glimepiride simultaneously targets insulin resistance and insulin deficiency in type 2 diabetes
Description:
Glimepiride 1mg + Metformin 500mg (Bi-Layer Tablet, Sustained Release) is a combination oral antidiabetic medication used in the treatment of type 2 diabetes mellitus. This bi-layer tablet formulation combines two complementary mechanisms of action to provide effective and sustained glycemic control:
Glimepiride (1mg): A sulfonylurea that increases insulin secretion from the pancreas.
Metformin (500mg SR): A biguanide that reduces hepatic glucose production and improves insulin sensitivity. The sustained-release (SR) formulation ensures gradual drug release for prolonged glucose control and better gastrointestinal tolerance.
The bi-layer design ensures that Glimepiride is released immediately for quick onset, while Metformin SR is released over an extended period for long-lasting action. This once-daily combination simplifies treatment and improves patient compliance.
Tags:
- Dual mechanism improves both insulin secretion and sensitivity
- Sustained-release Metformin ensures prolonged glucose control
- Bi-layer technology improves efficacy and minimizes GI side effects
- Convenient once-daily dosing enhances compliance
- Effective in reducing both fasting and postprandial blood glucose levels
Usage Information
Dosage
Typical Adult Dose: One tablet once daily with breakfast or first major meal. Dosage may be adjusted based on blood sugar levels and patient tolerance. Important: Do not crush or chew the tablet; swallow whole.
Side Effects
Common side effects: Hypoglycemia (especially if meals are skipped) Nausea, abdominal discomfort Diarrhea or flatulence (from Metformin) Headache or dizziness Serious side effects: Lactic acidosis (rare, from Metformin) Severe hypoglycemia (rare) Allergic skin reactions
Contraindications
Type 1 diabetes mellitus Diabetic ketoacidosis Severe renal or hepatic impairment History of lactic acidosis Hypersensitivity to Glimepiride, Metformin, or any excipients Acute conditions that may alter kidney function (e.g., dehydration, shock)
Availability
Glimepiride 1mg Metformin 500mg SR tablets Bi-layer diabetes tablet Type 2 diabetes combination therapy Metformin SR with Glimepiride Dual oral antidiabetic tablet Blood sugar control medicine Glimepiride Metformin sustained release Diabetes medicine once daily
