
SUGAMIDE-M-1
MRP: 735
Packaging: 10x15
Pack Type: tablet
Composition:
Glimepiride 1mg + Metformin 500mg (Bi Layer Tablet) (In SR)
Indication:
Metformin and glimepiride simultaneously targets insulin resistance and insulin deficiency in type 2 diabetes
Description:
This formulation combines Glimepiride 1 mg and Metformin Hydrochloride 500 mg in a bi-layer sustained release (SR) tablet, designed for effective and long-lasting glycemic control in adults with type 2 diabetes mellitus.
Glimepiride, a sulfonylurea, acts quickly to stimulate insulin secretion from pancreatic beta cells.
Metformin, a biguanide, works by reducing hepatic glucose production and increasing insulin sensitivity in peripheral tissues.
The bi-layer SR formulation ensures a dual-release mechanism: immediate release of Glimepiride for rapid onset of action and sustained release of Metformin for extended glucose control, improving therapeutic effectiveness and patient compliance.
This fixed-dose combination is recommended for patients not adequately controlled on monotherapy.
Tags:
- Dual-action control of blood glucose
- Bi-layer SR technology enhances treatment efficacy
- Reduces both fasting and postprandial blood sugar
- Once-daily dose improves compliance
- Ideal for patients uncontrolled on monotherapy
Usage Information
Dosage
Usual dose: One tablet once daily, preferably with breakfast Do not skip meals to avoid hypoglycemia Swallow whole; do not crush or chew Dosage may be adjusted based on glycemic response Follow your doctor’s prescription strictly
Side Effects
Hypoglycemia (low blood sugar symptoms like shakiness, sweating, confusion) Gastrointestinal issues (nausea, diarrhea, metallic taste – mostly due to Metformin) Weight gain (linked to Glimepiride) Skin rash or allergic reactions (rare) Lactic acidosis (rare but serious – mostly in renal impairment)
Contraindications
Type 1 diabetes mellitus Diabetic ketoacidosis Severe renal or hepatic impairment Known allergy to sulfonylureas or metformin Pregnant or lactating women (unless approved by a doctor) Conditions leading to hypoxia or dehydration (e.g., severe infections, heart failure)
Availability
Glimepiride 1 mg + Metformin 500 mg SR tablet Bi-layer diabetes medicine Sustained release antidiabetic tablet Type 2 diabetes combination therapy Glimepiride Metformin SR benefits Dual-action blood sugar control
