What is Sitagliptin + Metformin used for?

It is used to manage blood sugar levels in adults with type 2 diabetes mellitus.

Can I take this combination with insulin?

Yes, under medical supervision, it can be combined with insulin or other oral antidiabetics.

How should I take this medicine?

Take it with meals to reduce gastrointestinal side effects, usually once or twice daily as prescribed.

Does this medicine cause hypoglycemia?

Hypoglycemia is rare unless combined with sulfonylureas or insulin.

Can it be used in elderly patients?

Yes, but kidney function should be monitored regularly due to Metformin.

SITANOW-M 500 - Sitagliptin 50mg + Metformin Hydrochloride IP 500mg | Intralife Pharmaceuticals

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SITANOW-M 500

Name: SITANOW-M 500
Brand: Intralife
SKU: -O2iEMcBs6HMRSmE6DWc
Price: 2400 INR
Availability: InStock

MRP: 2,400

Packaging: 10x15

Pack Type: tablet

Composition:

Sitagliptin 50mg + Metformin Hydrochloride IP 500mg

Indication:

As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Description:

Sitagliptin 50mg + Metformin Hydrochloride IP 500mg is an oral combination antidiabetic medication used in the treatment of type 2 diabetes mellitus. Sitagliptin is a DPP-4 inhibitor that works by increasing incretin levels, thereby promoting insulin release and decreasing glucagon levels in the blood. Metformin, a biguanide, reduces glucose production in the liver and improves insulin sensitivity in peripheral tissues. This synergistic combination effectively lowers blood glucose levels and offers improved glycemic control, especially in patients inadequately managed by Metformin monotherapy or lifestyle modifications.

Usage Information

Dosage

Typical Adult Dose: One tablet (Sitagliptin 50mg + Metformin 500mg) once or twice daily with meals. Note: Dosage may vary based on clinical response. Always follow your healthcare provider's instructions.

Side Effects

Common side effects may include: Nausea, vomiting, diarrhea Flatulence or stomach discomfort Headache Upper respiratory tract infections Serious side effects (rare): Lactic acidosis (with Metformin) Pancreatitis (rare with Sitagliptin) Allergic reactions (rash, swelling)

Contraindications

Type 1 diabetes Diabetic ketoacidosis Severe kidney dysfunction or renal failure History of lactic acidosis Acute or chronic metabolic acidosis Hypersensitivity to Sitagliptin or Metformin

Availability

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Sitagliptin 50mg + Metformin 500mg Tablets | Intralife Pharmaceuticals | Intralife