SITANOW-M 100/1000 TABS
MRP: 1
Packaging: 10x10
Pack Type: tablet
Composition:
Sitagliptin (100mg) + Metformin (1000mg) SR
Indication:
for the management of type 2 diabetes mellitus in adults to improve glycemic control, especially when diet, exercise, and monotherapy are insufficient.
Description:
Sitagliptin 100 mg + Metformin HCl 1000 mg (SR) is a fixed-dose combination tablet used for the treatment of Type 2 Diabetes Mellitus (T2DM) in adults. It combines two complementary agents:
Sitagliptin, a DPP-4 inhibitor, enhances the levels of incretin hormones (GLP-1 and GIP), leading to increased insulin release and decreased glucagon levels in a glucose-dependent manner.
Metformin (1000 mg SR), a biguanide, lowers blood glucose by reducing hepatic glucose production and improving insulin sensitivity.
This combination helps to control both fasting and postprandial blood glucose levels with a low risk of hypoglycemia.
Tags:
- Dual mechanism for improved blood glucose control
- Controls fasting and post-meal glucose
- Low risk of hypoglycemia
- Cardiometabolic safety profile
- Extended-release metformin improves GI tolerance
Usage Information
Dosage
Recommended Dose: 1 tablet once daily with a meal (preferably evening) Do not crush or chew the SR tablet Dose may be adjusted based on glycemic response or physician’s discretion
Side Effects
Mild gastrointestinal issues: bloating, nausea, or diarrhea (usually from metformin) Headache or upper respiratory tract symptoms (from sitagliptin) Rare: Pancreatitis (seek immediate medical attention) Very rare: Lactic acidosis (from metformin, especially in renal impairment)
Contraindications
Type 1 diabetes mellitus Diabetic ketoacidosis (DKA) Severe renal impairment (eGFR < 30 mL/min/1.73m²) History of lactic acidosis Hypersensitivity to sitagliptin or metformin