
LINASUG-M 2.5/500
MRP: 1,650
Packaging: 10x10
Pack Type: tablet
Composition:
Linagliptin 2.5 mg, Metformin Hydrochloride IP 500 mg
Indication:
used along with diet and exercise and sometimes with other medications to lower blood sugar levels in patients with type 2 diabetes
Description:
Linagliptin 2.5 mg combined with Metformin Hydrochloride 500 mg is a potent oral antidiabetic medication formulated for adults with type 2 diabetes mellitus. This fixed-dose combination utilizes two complementary mechanisms:
Linagliptin is a DPP-4 inhibitor that enhances incretin hormones, leading to increased insulin secretion and decreased glucagon release, both in a glucose-dependent manner.
Metformin Hydrochloride is a biguanide that primarily reduces hepatic glucose production, improves insulin sensitivity, and enhances peripheral glucose uptake.
Together, they offer effective glycemic control by lowering fasting and postprandial blood glucose levels and reducing HbA1c. This combination is usually prescribed alongside diet and lifestyle modifications to optimize diabetes management.
Tags:
- Dual action for superior glycemic control
- Lowers HbA1c, fasting, and post-meal glucose
- Improves insulin sensitivity and secretion
- Weight neutral or may promote slight weight loss
- Convenient once or twice daily dosing
Usage Information
Dosage
Take one tablet twice daily or as prescribed Administer with meals to reduce gastrointestinal discomfort Follow healthcare provider’s instructions closely Do not skip or double doses
Side Effects
Gastrointestinal issues: nausea, diarrhea, abdominal pain Headache Hypoglycemia (especially with other antidiabetics) Vitamin B12 deficiency with long-term Metformin use Rare allergic reactions Seek immediate care if you experience severe allergic symptoms, lactic acidosis signs, or persistent GI upset.
Contraindications
Type 1 diabetes mellitus Diabetic ketoacidosis Severe renal impairment or metabolic acidosis Hypersensitivity to Linagliptin, Metformin, or any excipients Acute or chronic metabolic acidosis including lactic acidosis