DAPASUG-VM-500 TABS
MRP: 1
Packaging: 10X10
Pack Type: tablet
Composition:
DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE 10 mg VILDAGLIPTIN 100mg METFORMIN HYDROCHLORIDE IP 500mg (SR)
Indication:
Used to manage type 2 diabetes mellitus in adults when blood sugar is not controlled with dual therapy. It helps lower blood glucose by improving insulin action, increasing insulin release, and promoting glucose loss through urine. Ask ChatGPT
Description:
Triple Oral Therapy for Type 2 Diabetes**
This fixed-dose combination contains:
Dapagliflozin (10 mg) – An SGLT2 inhibitor that reduces glucose reabsorption in the kidneys, promoting glucose excretion via urine.
Vildagliptin (100 mg) – A DPP-4 inhibitor that enhances the body’s incretin system, stimulating insulin secretion and reducing glucagon release.
Metformin SR (500 mg) – A first-line biguanide that reduces hepatic glucose production and increases peripheral glucose uptake.
Together, they offer synergistic glycemic control, target multiple pathways, support weight management, and help reduce the risk of hypoglycemia.
Tags:
- Triple-action glucose control via different mechanisms
- Supports weight reduction and BP control (via dapagliflozin)
- Improves beta-cell responsiveness and insulin sensitivity
- Reduces HbA1c significantly
- Low risk of hypoglycemia when used appropriately
Usage Information
Dosage
Adults: 1 tablet once or twice daily, after meals, as directed by the physician Adjust dose based on blood sugar levels and renal function Maintain adequate hydration
Side Effects
Genitourinary infections (due to dapagliflozin) Headache, nasopharyngitis Gastrointestinal discomfort (metformin) Hypoglycemia (when used with sulfonylureas/insulin)
Contraindications
Severe renal impairment (eGFR < 30 mL/min) Type 1 Diabetes or diabetic ketoacidosis Known hypersensitivity to any of the ingredients Severe hepatic impairment Pregnancy and lactation (unless prescribed)