What is this combination used for?

It's used for managing Type 2 Diabetes when dual therapy is not sufficient.

How does this combination work?

It works by reducing glucose absorption, increasing insulin release, and improving insulin sensitivity.

Is this safe for long-term use?

Yes, under regular medical supervision with periodic glucose and kidney monitoring.

Can this be used as first-line therapy?

It’s generally used when initial treatments (like Metformin alone) fail to provide adequate control.

How should this be taken?

With meals to reduce stomach upset; once daily or as prescribed by your physician.

Triple combination for diabetes: Dapagliflozin + Sitagliptin | Intralife Pharmaceuticals

Name: DAPASUG-SM 1000 TABLETS
Brand: Intralife
SKU: -NzIBelcpicUVQXt5bEu
Price: 3150 INR
Availability: InStock

DAPASUG-SM 1000 TABLETS

MRP: 3,150

Packaging: 10x10

Pack Type: tablet

Composition:

Dapagliflozin 10mg + Sitagliptin 100mg + Metformin Hydrochloride IP 1000mg (Extended Release)

Indication:

Treatment of Type 2 Diabetes mellitus

Description:

Dapagliflozin 10 mg + Sitagliptin 100 mg + Metformin Hydrochloride 1000 mg (Extended Release)** is a triple combination oral antidiabetic therapy formulated to provide comprehensive glycemic control in patients with Type 2 Diabetes Mellitus.

This fixed-dose combination includes:

Dapagliflozin (10 mg): An SGLT2 inhibitor that promotes glucose excretion through urine.
Sitagliptin (100 mg): A DPP-4 inhibitor that enhances insulin secretion and reduces glucagon levels.
Metformin ER (1000 mg): A first-line insulin sensitizer that suppresses hepatic glucose production and improves peripheral glucose uptake.

Together, these three agents work synergistically to improve glycemic control, reduce insulin resistance, lower HbA1c, and support weight loss and cardiovascular health—especially beneficial for patients who require multidrug therapy.

Tags:

Type 2 Diabetes Triple Oral Therapy SGLT2 + DPP4 Inhibitor Extended Release Tablet Combination Antidiabetic

Usage Information

Dosage

Recommended Dose: One tablet daily or as prescribed Take with meals to minimize gastrointestinal discomfort Do not crush or chew; swallow whole Ensure adequate hydration Do not double dose if missed

Side Effects

Urinary tract or genital infections (Dapagliflozin) Headache, nausea, or abdominal discomfort (Metformin) Hypoglycemia (especially with other antidiabetics) Rare: Lactic acidosis (Metformin), ketoacidosis (Dapagliflozin) Upper respiratory tract infections (Sitagliptin)

Contraindications

Hypersensitivity to any component Type 1 Diabetes Mellitus or diabetic ketoacidosis Severe renal or hepatic impairment History of lactic acidosis Pregnancy and breastfeeding (without physician advice) Alcohol abuse or uncontrolled heart failure

Availability

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