DAPASUG-GM-1Tablet
MRP: 22
Packaging: 10x10
Pack Type: tablet
Composition:
Dapagliflozin 10mg + Glimepiride IP 2mg + Metformin Hydrochloride IP 1000mg (As extended release form)
Indication:
Patients with T2D with eCVD or multiple CV risk factors, to reduce the risk of hospitalization for heart failure
Description:
Dapagliflozin 10mg + Glimepiride IP 2mg + Metformin Hydrochloride IP 1000mg (Extended Release) is a potent fixed-dose triple combination tablet designed to manage type 2 diabetes mellitus. This combination incorporates three different classes of antidiabetic agents that work synergistically to improve blood glucose control:
Dapagliflozin (10mg): An SGLT2 inhibitor that reduces blood glucose by promoting urinary glucose excretion, also aiding in weight loss and cardiovascular benefits.
Glimepiride (2mg): A sulfonylurea that stimulates insulin secretion from pancreatic beta cells, reducing blood sugar levels.
Metformin Hydrochloride (1000mg, Extended Release): A biguanide that lowers hepatic glucose production and improves insulin sensitivity, with extended-release technology to minimize gastrointestinal side effects and provide sustained control.
This combination offers comprehensive glucose lowering by targeting multiple pathways — insulin secretion, insulin sensitivity, and glucose elimination — helping to reduce HbA1c, control fasting and postprandial glucose, and reduce diabetes complications.
Tags:
- Controls fasting and postprandial blood glucose levels
- Supports weight management and cardiovascular health
- Extended release Metformin reduces GI side effects
- Improves insulin secretion and sensitivity
- Convenient once-daily dosing enhances adherence
- Reduces HbA1c and risk of diabetes complications
Usage Information
Dosage
Take one tablet once daily with food or as directed by your healthcare provider Do not crush or chew the extended-release tablet Maintain regular meals to avoid hypoglycemia Monitor blood sugar regularly
Side Effects
Hypoglycemia (due to Glimepiride) Genital infections or urinary tract infections (due to Dapagliflozin) Gastrointestinal issues: nausea, diarrhea, abdominal discomfort Headache, dizziness Rare but serious: lactic acidosis (related to Metformin), dehydration, hypotension
Contraindications
Allergy to Dapagliflozin, Glimepiride, or Metformin Type 1 diabetes or diabetic ketoacidosis Severe renal or hepatic impairment History of lactic acidosis Pregnancy and breastfeeding without medical advice Recurrent urinary/genital infections
Availability
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