What is Tolvaptan 15mg used for?

It's used to treat low sodium levels and to slow the progression of ADPKD.

How does Tolvaptan work?

It blocks vasopressin V2 receptors in the kidneys, leading to water loss without losing sodium.

Is Tolvaptan safe for long-term use?

It may be used long-term for ADPKD but requires regular liver monitoring.

Can Tolvaptan be taken at home?

Initial doses are usually given in a hospital setting. Long-term use may be managed outpatient.

Does it cause frequent urination?

Yes, aquaresis is a common effect; maintain proper hydration.

Tolvaptan 15mg | Intralife Pharmaceuticals

Name: INTRATOL
Brand: Intralife
SKU: -NzIAK7AzQBgM4pB1qWN
Price: 5985 INR
Availability: InStock

INTRATOL

MRP: 5,985

Packaging: 10x1x4

Pack Type: tablet

Composition:

Tolvaptan 15mg

Indication:

In Treatment of Low levels of sodium in the blood, Low levels of sodium may be caused due to multiple reasons such as excess of body fluids, heart disease.

Description:

Tolvaptan 15mg is a vasopressin V2-receptor antagonist used to treat conditions associated with hyponatremia (low sodium levels), especially in patients with Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH), heart failure, or cirrhosis. It is also approved to slow the progression of autosomal dominant polycystic kidney disease (ADPKD).

Tolvaptan works by promoting free water excretion (aquaresis) without significant loss of sodium or potassium, thereby increasing serum sodium levels. It is a selective oral agent that offers a targeted and controlled correction of hyponatremia and is usually initiated in a hospital setting due to the need for close monitoring.

Tags:

Tolvaptan Vasopressin Antagonist Hyponatremia Treatment ADPKD Management Electrolyte Balance Kidney Health

Usage Information

Dosage

Starting dose: 15 mg once daily May be increased to 30–60 mg based on response and tolerance Take with or without food Do not consume grapefruit or grapefruit juice Ensure adequate fluid intake to prevent dehydration Initial dose should be administered under medical supervision

Side Effects

Frequent urination (polyuria) Thirst or dry mouth Nausea Fatigue or dizziness Elevated liver enzymes (monitor regularly) Risk of too-rapid correction of sodium (requires monitoring)

Contraindications

Patients unable to sense or respond to thirst Anuria (no urine output) Significant liver impairment or liver disease Concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole) Pregnancy and lactation (unless clearly needed) Hypersensitivity to Tolvaptan