
INTRABON
MRP: 7,990
Packaging: 10x1x10
Pack Type: tablet
Composition:
Bosentan 62.5mg
Indication:
Pulmonary arterial hypertension
Description:
Bosentan 62.5 mg is an endothelin receptor antagonist used primarily in the treatment of pulmonary arterial hypertension (PAH). It works by blocking endothelin-1, a substance in the blood vessels that causes them to narrow. By inhibiting its action, Bosentan helps relax and widen blood vessels, thereby improving blood flow and lowering blood pressure in the lungs. This eases the workload on the heart and enhances a patient’s ability to exercise. It is generally prescribed for adults and children over the age of 12 diagnosed with WHO Group I PAH.
Tags:
- Treats pulmonary arterial hypertension (PAH) effectively
- Improves exercise capacity
- Lowers pulmonary blood pressure
- Helps reduce symptoms like breathlessness and fatigue
- Delays progression of PAH
- Enhances overall cardiovascular function
Usage Information
Dosage
Standard Adult Dose: 62.5 mg twice daily for 4 weeks, then increased to 125 mg twice daily as tolerated. Administration: Oral; with or without food. Missed Dose: Take as soon as remembered unless it’s close to the next dose. Overdose: Seek immediate medical attention if overdose is suspected. Note: Always follow the exact dosage prescribed by your healthcare provider.
Side Effects
Common Side Effects: Headache Respiratory tract infections Flushing Nasal congestion Edema (swelling of the legs or ankles) Serious Side Effects: Elevated liver enzymes Anemia Low blood pressure Liver dysfunction Reduced sperm count in men Seek immediate medical help if signs of liver issues (fatigue, nausea, dark urine, jaundice) appear.
Contraindications
Pregnancy (Category X – Teratogenic risk) Severe liver impairment or elevated liver enzymes Concomitant use with cyclosporine A Hypersensitivity to Bosentan or any component of the formulation Breastfeeding women Patients with moderate to severe anemia
Availability
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